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PRX-08066
CAS No. 866206-54-4
PRX-08066( —— )
Catalog No. M24869 CAS No. 866206-54-4
PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 107 | In Stock |
|
| 5MG | 116 | In Stock |
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| 10MG | 169 | In Stock |
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| 25MG | 351 | In Stock |
|
| 50MG | 511 | In Stock |
|
| 100MG | 733 | In Stock |
|
| 200MG | 1004 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePRX-08066
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NoteResearch use only, not for human use.
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Brief DescriptionPRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
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DescriptionPRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT2B
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Research Area——
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Indication——
Chemical Information
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CAS Number866206-54-4
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Formula Weight401.89
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Molecular FormulaC19H17ClFN5S
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Purity>98% (HPLC)
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SolubilityDMSO:7 mg/mL (17.42 mM; Need ultrasonic)
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SMILESC1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Porvasnik SL, et al. PRX-08066, a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. J Pharmacol Exp Ther. 2010 Aug;334(2):364-72.
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