Auxinole
CAS No. 86445-22-9
Auxinole( —— )
Catalog No. M24866 CAS No. 86445-22-9
Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex . It inhibits auxin-responsive gene expression.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 82 | In Stock |
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| 5MG | 71 | In Stock |
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| 10MG | 103 | In Stock |
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| 25MG | 170 | In Stock |
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| 50MG | 246 | In Stock |
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| 100MG | 369 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 879 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAuxinole
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NoteResearch use only, not for human use.
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Brief DescriptionAuxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex . It inhibits auxin-responsive gene expression.
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DescriptionAuxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex . It inhibits auxin-responsive gene expression.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorTIR1/AFB receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number86445-22-9
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Formula Weight321.37
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Molecular FormulaC20H19NO3
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (388.96 mM);Ethanol:12.5 mg/mL (38.90 mM; Need ultrasonic)
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SMILESCc(cc1)cc(C)c1C(CC(C(O)=O)c1c[nH]c2c1cccc2)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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HLM006474
HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 μM in A375 cells).HLM006474 causes the viability of both SCLC and NSCLC lines (IC50 ranging from 15 to 75 μM). HLM006474 displays little activities against E2F4 DNA-binding in A375 cells at 10 and 20 μM, apparently inhibits E2F4 DNA-binding at 40 μM, and increasingly suppresses the effect at 60 and 80 μM concentrations.
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IGS-1.76
IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently.IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex.IGS-1.76, which efficiently inhibits the human NCS-1/Ric8a complex with improved binding potency.?
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gp38
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