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Miglustat
CAS No. 72599-27-0
Miglustat( N-Butyldeoxynojirimycin | NB-DNJ | OGT918 )
Catalog No. M24736 CAS No. 72599-27-0
Miglustat is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 93 | In Stock |
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| 5MG | 85 | In Stock |
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| 10MG | 132 | In Stock |
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| 25MG | 245 | In Stock |
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| 50MG | 398 | In Stock |
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| 100MG | 579 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMiglustat
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NoteResearch use only, not for human use.
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Brief DescriptionMiglustat is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).
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DescriptionMiglustat is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).
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In Vitro——
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In VivoAnimal Model:NPC1?/? mice Dosage:0.2?mg/kg Administration:Oral administration; once Result:Was able to rescue synaptic plasticity deficits, to restore ERKs activation and to counteract hyperexcitability.
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SynonymsN-Butyldeoxynojirimycin | NB-DNJ | OGT918
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number72599-27-0
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Formula Weight219.28
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Molecular FormulaC10H21NO4
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESO[C@H]1[C@H](O)[C@@H](CO)N(CCCC)C[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Abian, O., et al., Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase. Mol Pharm, 2011. 8(6): p. 2390-7.
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