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ARP-100
CAS No. 704888-90-4
ARP-100( MMP-2 Inhibitor III | ARP100 )
Catalog No. M24720 CAS No. 704888-90-4
ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM)
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 58 | In Stock |
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| 10MG | 88 | In Stock |
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| 25MG | 178 | In Stock |
|
| 50MG | 335 | In Stock |
|
| 100MG | 537 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameARP-100
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NoteResearch use only, not for human use.
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Brief DescriptionARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM)
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DescriptionARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM).
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In VitroARP-100 (50 nM) shows a significant reduction in the total number of invasive elongations.
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In Vivo——
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SynonymsMMP-2 Inhibitor III | ARP100
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PathwayMetabolic Enzyme/Protease
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TargetMMP
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RecptorMMP-2|MMP-9|MMP-3|MMP-1|MMP-7
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Research Area——
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Indication——
Chemical Information
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CAS Number704888-90-4
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Formula Weight364.42
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Molecular FormulaC17H20N2O5S
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Purity>98% (HPLC)
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SolubilityDMSO:96 mg/mL?(263.43 mM;?Need ultrasonic)
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SMILESCC(C)ON(CC(NO)=O)S(c(cc1)ccc1-c1ccccc1)(=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Rossello A, et al. New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2). Bioorg Med Chem. 2004 May 1;12(9):2441-50.
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