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Mulberrin

CAS No. 62949-79-5

Mulberrin( Kuwanon C )

Catalog No. M24630 CAS No. 62949-79-5

Mulberrin is an inhibitor of OATP2B1-mediated estrone-3-sulfate (E3S) uptake (IC50: 1.8 ±1.5 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Mulberrin
  • Note
    Research use only, not for human use.
  • Brief Description
    Mulberrin is an inhibitor of OATP2B1-mediated estrone-3-sulfate (E3S) uptake (IC50: 1.8 ±1.5 μM).
  • Description
    Mulberrin is an inhibitor of OATP2B1-mediated estrone-3-sulfate (E3S) uptake (IC50: 1.8 ±1.5 μM).
  • In Vitro
    Mulberrin is a flavone with two isopentenyl groups at positions 3 and 8. Mulberrin is a strong inhibitor of OATP2B1 with more than 80% inhibition.Mulberrin also inhibits organic anion-transporting polypeptide (OATP)-mediated uptake of Atorvastatin, Fluvastatin, and Rosuvastatin.
  • In Vivo
    ——
  • Synonyms
    Kuwanon C
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    62949-79-5
  • Formula Weight
    422.47
  • Molecular Formula
    C25H26O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble
  • SMILES
    C/C(C)=C\CC1=C2C(C(C(C/C=C(C)\C)=C(C3=C(C=C(O)C=C3)O)O2)=O)=C(O)C=C1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wen F, et al. Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify OATP-mediated uptake. Pharm Biol. 2016;54(2):293-302.
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