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Bifemelane hydrochloride
CAS No. 62232-46-6
Bifemelane hydrochloride( —— )
Catalog No. M24622 CAS No. 62232-46-6
Bifemelane hydrochloride is a MAO inhibitor
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 37 | In Stock |
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| 5MG | 33 | In Stock |
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| 10MG | 55 | In Stock |
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| 25MG | 112 | In Stock |
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| 50MG | 182 | In Stock |
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| 100MG | 277 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 603 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBifemelane hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionBifemelane hydrochloride is a MAO inhibitor
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DescriptionBifemelane hydrochloride is a MAO inhibitor.
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In VitroBifemelane inhibits MAO-A in a dose-dependent manner, with Kis of 4.2±0.2 and 14.1±0.7 μM in human brain synaptosomes and human liver mitochondria respectively.Bifemelane inhibits MAO-B activities in a dose-dependent manner, with Kis of 46.0±3.6 and 65.2±7.0 μM in human brain synaptosomes and human liver mitochondria respectively.
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In VivoBifemelane (20-80 mg/kg; i.p.) dose-dependently decreases exploratory activity in the open field test.Bifemelane (20-80 mg/kg; i.p.) decreases immobility time in the forced swim test, although is not clearly dosedependent and has already reached ceiling at 20 mg/kg. Animal Model:Wistar male rats (230-270 g) are induced hypothermia by ReserpineDosage:20, 40, 80 mg/kg Administration:A single i.p. Result:Attenuated the Reserpine-induced hypothermia by a maximum of 10 ℃.
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetMAO
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RecptorMAO
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Research Area——
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Indication——
Chemical Information
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CAS Number62232-46-6
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Formula Weight305.84
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Molecular FormulaC18H23NO·HCl
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Purity>98% (HPLC)
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SolubilityH2O:<30.58mg/ml;DMSO:<30.58mg/ml
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SMILESCNCCCCOC1=CC=CC=C1CC2=CC=CC=C2.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yoshida Y , Kumagai H , Ohkubo Y , et al. Effects of bifemelane on the calcium level and ATP release of the human origin astrocyte clonal cell.[J]. Journal of Pharmacological Sciences, 2006, 102(1):121-128.
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