Sodium citrate dihydrate

CAS No. 6132-04-3

Sodium citrate dihydrate( Trisodium citrate dihydrate | Citric acid trisodium salt dihydrate )

Catalog No. M24612 CAS No. 6132-04-3

Sodium citrate dihydrate is an anticoagulant, and also used as a buffer and food preservatives.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Sodium citrate dihydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Sodium citrate dihydrate is an anticoagulant, and also used as a buffer and food preservatives.
  • Description
    Sodium citrate dihydrate is an anticoagulant, and also used as a buffer and food preservatives.
  • In Vitro
    Cell Viability Assay Cell Line:MGC-803 Concentration:1.25, 2.5, 5, 10,15, 20, 30, 40, 60 mM Incubation Time:24, 48 h Result:Decreased cell viability in a dose-and time-dependent manner.The IC50 value is 10.08 mM after 48 h.Apoptosis Analysis Cell Line:MGC-803 Concentration:5, 10, 20 mM Incubation Time:24 h Result:Decreased the mRNA and protein expressions of anti-apoptotic Bcl-2 and Survivin.Increased the mRNA and protein expression level of proapoptotic Bax, caspase-3 and Cyt-c.Western Blot Analysis Cell Line:MGC-803Concentration:5, 10, 20 mM Incubation Time:24, 48 h Result:Induced cell apoptosis in a dose-and time-dependent manner.Increased the G2/M phase arrest.
  • In Vivo
    Animal Model:Adenine-Induced Chronic Renal Failure Rat ModelDosage:216, 746 mg/kg Administration: i.g.Result:Decreased the expression of renal fibrosis-related proteins TGF-β1 and CIV.Decreased the expression of PERK, ATF6 and CHOP.
  • Synonyms
    Trisodium citrate dihydrate | Citric acid trisodium salt dihydrate
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Bacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6132-04-3
  • Formula Weight
    294.1
  • Molecular Formula
    C6H9Na3O9
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:125 mg/mL (425.03 mM; Need ultrasonic)
  • SMILES
    C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.O.O.[Na+].[Na+].[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Adcock DM, et al. Effect of 3.2% vs 3.8% sodium citrate concentration on routine coagulation testing. Am J Clin Pathol. 1997 Jan;107(1):105-10.
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