Terminolic acid( 2α,6β,23-trihydroxyl oleanolic acid )

Catalog No. M24552 CAS No. 564-13-6

Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum, can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	162	In Stock
5MG	106	In Stock
10MG	155	In Stock
25MG	258	In Stock
50MG	365	In Stock
100MG	547	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Terminolic acid
Note

Research use only, not for human use.
Brief Description

Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum, can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites.
Description

Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum, can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites. It also exhibits moderate antibacterial activity.
In Vitro

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In Vivo

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Synonyms

2α,6β,23-trihydroxyl oleanolic acid
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Bacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

564-13-6
Formula Weight

504.7
Molecular Formula

C30H48O6
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

C[C@@]12CC[C@]3(CCC(C[C@H]3C1=CC[C@H]4[C@]2(C[C@H]([C@@H]5[C@@]4(C[C@H]([C@@H]([C@@]5(C)CO)O)O)C)O)C)(C)C)C(=O)O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Legiawati L, et, al. In silico study of Centella asiatica active compounds as anti-inflammatory agent by decreasing Il-1 and Il-6 activity, promoting Il-4 activity. /J. Pharm. Sci. & Res. Vol. 10(9), 2018, 2142-2147.

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