Deltamethrin

Research use only, not for human use.

Deltamethrin (Decamethrin), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.

Deltamethrin (Decamethrin), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, control of malaria and other vector-borne diseases. It is easily degradable.

Cell Viability Assay Cell Line:Murine thymocytes Concentration:0.5 μM, 1 μM, 10 μM, 25 μM, 50 μM, 100 μM Incubation Time:6 h, 18 h Result:Caused 32% and 59% loss in cell viability at 25 μM and 100 μM at 6 h.Caused 46% and 68% loss in cell viability at 25 μM and 100 μM at 18 h.Cell Cycle Analysis Cell Line:Murine thymocytes Concentration:10 μM, 25 μM, 50 μM Incubation Time:18 h Result:Increased the number of apoptotic cells in a concentration-dependent manner.

Animal Model:Swiss albino male miceDosage:5.6 mg/kg, 18 mg/kg Administration:OralResult:Significantly induced lipid peroxidation (LPO) in liver and kidney.Suppressed the activities of vital antioxidant enzymes such as glutathione peroxidase (GPx), glutathione S-transferase (GST) and catalase (CAT).Decreased the glutathione (GSH) level.Animal Model:Male Sprague-Dawley rats Dosage:60 mg/kg Administration:Intraperitoneal injection (i.p.) Result:Modulated the hippocampal high-affinity choline uptake (HACU).Increased the activity of ChAT in the hippocampus and cortex.Increased the activity of striatal ChAT.

Butoss | Decamethrin | Esbecythrin | K-Othrin | RU 22974 | RU-22974

Others

Other Targets

Others

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52918-63-5

505.2

C22H19Br2NO3

>98% (HPLC)

DMSO:Soluble

O=C([C@H]1C(C)(C)[C@H]1/C=C(Br)\Br)O[C@H](C#N)C2=CC=CC(OC3=CC=CC=C3)=C2

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(-20℃)

With Ice Pack

≥ 2 years