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5-Hydroxymethyldeoxyuridine
CAS No. 5116-24-5
5-Hydroxymethyldeoxyuridine( —— )
Catalog No. M24477 CAS No. 5116-24-5
5-Hydroxymethyldeoxyuridine is an analog of nucleoside that has anticancer and antiviral activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 44 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 39 | In Stock |
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| 25MG | 63 | In Stock |
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| 50MG | 108 | In Stock |
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| 100MG | 184 | In Stock |
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| 200MG | 277 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name5-Hydroxymethyldeoxyuridine
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NoteResearch use only, not for human use.
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Brief Description5-Hydroxymethyldeoxyuridine is an analog of nucleoside that has anticancer and antiviral activities.
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Description5-Hydroxymethyldeoxyuridine is an analog of nucleoside that has anticancer and antiviral activities. It suppresses the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM).
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In Vitro5-Hydroxymethyl-2'-deoxyuridine (0-10 μM) inhibits the replication of Sarcoma 180 cells and Ehrlich ascites carcinoma cells with ED50 values of 8.5 and 4 μM, respectively. 5-Hydroxymethyl-2'-deoxyuridine inhibits herpes simplex virus type 1 (HSV-1) pyrimidine 2’-deoxyribonucleoside kinase with a Ki value of 3.5 μM.5-Hydroxymethyl-2'-deoxyuridine inhibits the replication of multiple human leukemia cell lines with IC50 values of 1.7-5.8 μM.5-Hydroxymethyl-2'-deoxyuridine (10-100 μM) shows dose-dependent toxicity against a human acute promyelocytic leukemia cell line.
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In Vivo5-Hydroxymethyl-2'-deoxyuridine (0, 5 and 50 mg/kg; i.p.; once) increases the survival of DBA/2 mice carrying L1210 leukemia.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptorothers
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Research Area——
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Indication——
Chemical Information
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CAS Number5116-24-5
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Formula Weight258.23
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Molecular FormulaC10H14N2O6
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Purity>98% (HPLC)
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SolubilityDMSO:Soluble
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SMILESOC[C@H]([C@H](C1)O)O[C@H]1N(C=C(CO)C(N1)=O)C1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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(S)-armepavine
(+)-Armepavine is a bioactive compound with pharmacological activity. As an alkaloid, (+)-Armepavine belongs to the tetrahydrobenzylisoquinoline class of compounds and may play a role in inhibiting certain diseases. The chemical structure and properties of (+)-Armepavine make it an important chemical classification in phytochemistry.
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CQ211
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SXC 2023
SXC 2023 ((S)-2-acetamido-3-(4-methylbenzoylthio)propanoic acid) is a therapeutic prodrug of N-acetyl-L-cysteine for the treatment of CNS disorders and neurocognitive disorders, and can be used to treat glutamatergic dysfunction and psychiatric disorders in which oxidative stress plays a key role.
