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5-hydroxytryptamine

CAS No. 50-67-9

5-hydroxytryptamine( —— )

Catalog No. M24470 CAS No. 50-67-9

5-hydroxytryptamine is a natural product from animals.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 38 In Stock
2MG 29 In Stock
5MG 48 In Stock
10MG 78 In Stock
25MG 160 In Stock
50MG 258 In Stock
100MG 418 In Stock
200MG 604 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    5-hydroxytryptamine
  • Note
    Research use only, not for human use.
  • Brief Description
    5-hydroxytryptamine is a natural product from animals.
  • Description
    5-hydroxytryptamine is a natural product from animals.
  • In Vitro
    Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin also inhibits catechol O-methyltransferase (COMT), an enzyme that contributes to modultion the perception of pain, via non-competitive binding to the site bound by catechol substrates with a binding affinity comparable to the binding affinity of catechol itself (Ki=?44 μM). Results show that addition of 100 μM of Serotonin decreases the reaction velocity of COMT.
  • In Vivo
    Serotonin produces robust hypersensitivity compare to saline-treated controls (p<0.001). A significant increase in colonic 5-HT content is observed in IL-13-/- mice receiving Serotonin compare to IL-13-/- receiving vehicle following induction of DSS colitis.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    50-67-9
  • Formula Weight
    176.22
  • Molecular Formula
    C10H12N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (567.47 mM)
  • SMILES
    NCCc1c[nH]c(cc2)c1cc2O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sigal Rozenblit㏒usan, Chapnik N , Froy O . Serotonin Prevents Differentiation of Brown Adipocytes by Interfering with Their Clock[J]. Obesity, 2019, 27(12).
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