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SU3327
CAS No. 40045-50-9
SU3327( —— )
Catalog No. M24361 CAS No. 40045-50-9
SU3327 is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 85 | In Stock |
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| 2MG | 30 | In Stock |
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| 5MG | 56 | In Stock |
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| 10MG | 92 | In Stock |
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| 25MG | 174 | In Stock |
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| 50MG | 305 | In Stock |
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| 100MG | 462 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSU3327
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NoteResearch use only, not for human use.
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Brief DescriptionSU3327 is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).
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DescriptionSU3327 is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).
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In Vitro——
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In VivoAnimal Model:Male BKS.Cg-+Leprdb/+Leprdb/OlaHsd db/db mice (11-week-old ) injected with insulin Dosage:25 mg/kg Administration:Intraperitoneal injection Result:Resulted in a statistically significant reduction in blood glucose levels.
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Synonyms——
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PathwayMAPK/ERK Signaling
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TargetJNK
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RecptorJNK|JNK-JIP interactions
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Research Area——
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Indication——
Chemical Information
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CAS Number40045-50-9
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Formula Weight261.3
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Molecular FormulaC5H3N5O2S3
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Purity>98% (HPLC)
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SolubilityDMSO:62.5 mg/mL (239.19 mM; Need ultrasonic)
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SMILESNc1nnc(Sc2ncc([N+]([O-])=O)s2)s1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.De SK, et al. Design, synthesis, and structure-activity relationship of substrate competitive, selective, and in vivo active triazole and thiadiazole inhibitors of the c-Jun N-terminal kinase. J Med Chem. 2009 Apr 9;52(7):1943-52.
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