2-tert-Butyl-1,4-benzoquinone( —— )

Catalog No. M24318 CAS No. 3602-55-9

2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), causes activation of Nrf2 together with S-arylation of its negative regulator Keap1 in RAW264.7 cells.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

2-tert-Butyl-1,4-benzoquinone
Note

Research use only, not for human use.
Brief Description

2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), causes activation of Nrf2 together with S-arylation of its negative regulator Keap1 in RAW264.7 cells.
Description

2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), causes activation of Nrf2 together with S-arylation of its negative regulator Keap1 in RAW264.7 cells.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Nuclear Receptor/Transcription Factor
Target

Keap1-Nrf2
Recptor

Nrf2
Research Area

——
Indication

——

Chemical Information

CAS Number

3602-55-9
Formula Weight

164.2
Molecular Formula

C10H12O2
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(C)(C)C(C(C=C1)=O)=CC1=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Abiko Y, Kumagai Y. Interaction of Keap1 modified by 2-tert-butyl-1,4-benzoquinone with GSH: evidence for S-transarylation. Chem Res Toxicol. 2013 Jul 15;26(7):1080-7.

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