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Maytansine

CAS No. 35846-53-8

Maytansine( NSC153858 | NSC 153858 | NSC-153858 | maytansine | Maitansine | Maitansina )

Catalog No. M24313 CAS No. 35846-53-8

Maytansine, an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 83 In Stock
5MG 53 In Stock
10MG 73 In Stock
25MG 174 In Stock
100MG Get Quote In Stock
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Biological Information

  • Product Name
    Maytansine
  • Note
    Research use only, not for human use.
  • Brief Description
    Maytansine, an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
  • Description
    Maytansine, an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
  • In Vitro
    Maytansine, at 6x10-8 M, irreversibly inhibits cell division in eggs of sea urchins and clams. Maytansine causes the disappearance of a mitotic apparatus or prevents one from forming if added at early stages. Maytansine inhibits in vitro polymerization of tubulin.
  • In Vivo
    ——
  • Synonyms
    NSC153858 | NSC 153858 | NSC-153858 | maytansine | Maitansine | Maitansina
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    Antibiotic|microtubule
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    35846-53-8
  • Formula Weight
    692.2
  • Molecular Formula
    C34H46ClN3O10
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble; Water:Insoluble
  • SMILES
    CC(C(OC(CC(N(C)c1cc(CC(C)=CC=CC(C(C2)(N3)O)OC)cc(OC)c1Cl)=O)C1(C)OC1C(C)C2OC3=O)=O)N(C)C(C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kusari S, Lamsh?ft M, Kusari P, Gottfried S, Zühlke S, Louven K, Hentschel U, Kayser O, Spiteller M. Endophytes are hidden producers of maytansine in Putterlickia roots. J Nat Prod. 2014 Dec 26;77(12):2577-84.
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