Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - DNA/RNA Synthesis - BVDV-IN-1

BVDV-IN-1

CAS No. 345651-04-9

BVDV-IN-1( —— )

Catalog No. M24294 CAS No. 345651-04-9

BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 87 In Stock
5MG 79 In Stock
10MG 126 In Stock
25MG 255 In Stock
50MG 367 In Stock
100MG 524 In Stock
200MG 710 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    BVDV-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp.
  • Description
    BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC).
  • In Vitro
    BVDV-IN-1 (compound 1.9) binds to a hydrophobic pocket of the BVDV RNA-dependent RNA polymerase (RdRp).BVDV-IN-1 inhibits the replication of TSC-resistant BVDV variants in vitro.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    345651-04-9
  • Formula Weight
    334.42
  • Molecular Formula
    C20H22N4O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 250 mg/mL (747.59 mM; Need ultrasonic)
  • SMILES
    OCCN1CCN(C2=C3C=CC=CC3=NC(C4=CC=CC=C4)=N2)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gabriela A Fernández, et al. Design and Optimization of Quinazoline Derivatives: New Non-nucleoside Inhibitors of Bovine Viral Diarrhea Virus. Front Chem. 2020 Dec 10;8:590235.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • TMPyP4 tosylate

    TMPyP4 tosylate is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.

  • ML-60218

    ML-60218 (ML60218)?is a broad-spectrum, small molecule inhibitor of RNA polymerase (Pol) III with IC50 of 32 and 27 uM for Saccharomyces cerevisiae and human, respectively.

  • NITD-2

    NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation.?

Sign In Join Free