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BVDV-IN-1
CAS No. 345651-04-9
BVDV-IN-1( —— )
Catalog No. M24294 CAS No. 345651-04-9
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 87 | In Stock |
|
| 5MG | 79 | In Stock |
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| 10MG | 126 | In Stock |
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| 25MG | 255 | In Stock |
|
| 50MG | 367 | In Stock |
|
| 100MG | 524 | In Stock |
|
| 200MG | 710 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBVDV-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionBVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp.
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DescriptionBVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC).
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In VitroBVDV-IN-1 (compound 1.9) binds to a hydrophobic pocket of the BVDV RNA-dependent RNA polymerase (RdRp).BVDV-IN-1 inhibits the replication of TSC-resistant BVDV variants in vitro.
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA/RNA Synthesis
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Research Area——
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Indication——
Chemical Information
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CAS Number345651-04-9
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Formula Weight334.42
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Molecular FormulaC20H22N4O
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Purity>98% (HPLC)
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SolubilityDMSO : 250 mg/mL (747.59 mM; Need ultrasonic)
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SMILESOCCN1CCN(C2=C3C=CC=CC3=NC(C4=CC=CC=C4)=N2)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Gabriela A Fernández, et al. Design and Optimization of Quinazoline Derivatives: New Non-nucleoside Inhibitors of Bovine Viral Diarrhea Virus. Front Chem. 2020 Dec 10;8:590235.
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