GSK-3β inhibitor 1 (b)
CAS No. 3367-88-2
GSK-3β inhibitor 1 (b)( —— )
Catalog No. M24282 CAS No. 3367-88-2
GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 115 | In Stock |
|
| 10MG | 192 | In Stock |
|
| 25MG | 354 | In Stock |
|
| 50MG | 530 | In Stock |
|
| 100MG | 759 | In Stock |
|
| 500MG | 1557 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGSK-3β inhibitor 1 (b)
-
NoteResearch use only, not for human use.
-
Brief DescriptionGSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.
-
DescriptionGSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayPI3K/Akt/mTOR signaling
-
TargetGSK-3
-
RecptorGSK-3β
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number3367-88-2
-
Formula Weight222.24
-
Molecular FormulaC14H10N2O
-
Purity>98% (HPLC)
-
SolubilityDMSO:49 mg/mL?(220.48 mM;?Need ultrasonic)
-
SMILESO=C1Nc(cccc2)c2C1=Cc1ncccc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.
molnova catalog
related products
-
CHIR-99021 trihydroc...
A potent, specific GSK-3 inhibitor with IC50 of 5 nM and 10 nM for GSK3β and GSK3α, respectively.
-
GSK-3β inhibitor 1
GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.GSK-3β inhibitor 1(compound 3a) inhibits GSK-3β with IC50 4.19 nM.?In a cell-based assay 3a shows no significant leucocyte toxicity at 10 M and is moderately cytotoxic against A549 cells.?
-
AZD1080
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively.
Cart
sales@molnova.com