ML SA1

CAS No. 332382-54-4

ML SA1( Mucolipin synthetic agonist 1 )

Catalog No. M24271 CAS No. 332382-54-4

ML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 50 In Stock
2MG 29 In Stock
5MG 45 In Stock
10MG 70 In Stock
25MG 145 In Stock
50MG 238 In Stock
100MG 356 In Stock
200MG 538 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ML SA1
  • Note
    Research use only, not for human use.
  • Brief Description
    ML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity.
  • Description
    ML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively.
  • In Vitro
    Western Blot Analysis Cell Line:A549 cells Concentration:25 μM Incubation Time:0~14 hours Result:Possibly affected the entry of DENV2 into host cells.
  • In Vivo
    ——
  • Synonyms
    Mucolipin synthetic agonist 1
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TRPML
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    332382-54-4
  • Formula Weight
    362.42
  • Molecular Formula
    C22H22N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:17 mg/mL (46.90 mM)
  • SMILES
    CC(CC1(C)C)c(cccc2)c2N1C(CN(C(c1c2cccc1)=O)C2=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xia Z, et al. ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity. Antiviral Res. 2020;182:104922.
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