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ML SA1
CAS No. 332382-54-4
ML SA1( Mucolipin synthetic agonist 1 )
Catalog No. M24271 CAS No. 332382-54-4
ML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 45 | In Stock |
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| 10MG | 70 | In Stock |
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| 25MG | 145 | In Stock |
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| 50MG | 238 | In Stock |
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| 100MG | 356 | In Stock |
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| 200MG | 538 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML SA1
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NoteResearch use only, not for human use.
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Brief DescriptionML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity.
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DescriptionML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively.
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In VitroWestern Blot Analysis Cell Line:A549 cells Concentration:25 μM Incubation Time:0~14 hours Result:Possibly affected the entry of DENV2 into host cells.
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In Vivo——
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SynonymsMucolipin synthetic agonist 1
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PathwayOthers
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TargetOther Targets
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RecptorTRPML
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Research Area——
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Indication——
Chemical Information
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CAS Number332382-54-4
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Formula Weight362.42
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Molecular FormulaC22H22N2O3
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Purity>98% (HPLC)
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SolubilityDMSO:17 mg/mL (46.90 mM)
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SMILESCC(CC1(C)C)c(cccc2)c2N1C(CN(C(c1c2cccc1)=O)C2=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Xia Z, et al. ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity. Antiviral Res. 2020;182:104922.
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