Cart
sales@molnova.com
ML SA1
CAS No. 332382-54-4
ML SA1( Mucolipin synthetic agonist 1 )
Catalog No. M24271 CAS No. 332382-54-4
ML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
|
| 2MG | 29 | In Stock |
|
| 5MG | 45 | In Stock |
|
| 10MG | 70 | In Stock |
|
| 25MG | 145 | In Stock |
|
| 50MG | 238 | In Stock |
|
| 100MG | 356 | In Stock |
|
| 200MG | 538 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameML SA1
-
NoteResearch use only, not for human use.
-
Brief DescriptionML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity.
-
DescriptionML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively.
-
In VitroWestern Blot Analysis Cell Line:A549 cells Concentration:25 μM Incubation Time:0~14 hours Result:Possibly affected the entry of DENV2 into host cells.
-
In Vivo——
-
SynonymsMucolipin synthetic agonist 1
-
PathwayOthers
-
TargetOther Targets
-
RecptorTRPML
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number332382-54-4
-
Formula Weight362.42
-
Molecular FormulaC22H22N2O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:17 mg/mL (46.90 mM)
-
SMILESCC(CC1(C)C)c(cccc2)c2N1C(CN(C(c1c2cccc1)=O)C2=O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Thalidezine
Thalidezine is a novel activator of AMP-activated protein kinase (AMPK). Thalidezine can eliminate anti-apoptotic cancer cells through energy-mediated autophagy death. Thalidezine can be used to study apoptosis intervention .
-
RGD-4C
RGD-4C is a arginine-glycine-aspartic acid peptide (ACDCRGDCFC) with integrin binding activity. The Arg-Gly-Asp (RGD) sequence serves as the primary integrin recognition site in extracellular matrix proteins, and peptides containing this sequence can mimic the recognition specificity of the matrix proteins. RGD-4C is a αv-integrin ligand, can conjugate with bioactive molecule to exert antitumor effects in animal models.
-
Acitemate
Acitemate(Chinoin 123) has an inhibitory effect on atherosclerosis and reduces the permeability of the aorta in rabbits fed a hyperlipidemic diet, which can be used to study atherosclerosis.
