Cart
sales@molnova.com
Mecillinam
CAS No. 32887-01-7
Mecillinam( Amdinocillin | AMDINOCILLIN | Coactin | Penicillin HX | Mecillinamum | Hexacillin )
Catalog No. M24265 CAS No. 32887-01-7
Mecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | In Stock |
|
| 10MG | 33 | In Stock |
|
| 25MG | 50 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMecillinam
-
NoteResearch use only, not for human use.
-
Brief DescriptionMecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2).
-
DescriptionMecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2). It is used primarily to treat urinary tract infections and has also been used in the treatment of paratyphoid fever and typhoid.
-
In Vitro——
-
In VivoAnimal Model:Mecillinam (Amdinocillin, 400 mg per kg) is effective for the treatment of catheterassociated infections at high dosages (400 mg per kg of body weight/d).Dosage:50, 100, 200, and 400 mg per kg. Administration:Intravenously each day in four divided doses over a 72-h period.Result:High dose of 400 mg/kg exhibited significant activity.
-
SynonymsAmdinocillin | AMDINOCILLIN | Coactin | Penicillin HX | Mecillinamum | Hexacillin
-
PathwayGPCR/G Protein
-
TargetAntibacterial
-
RecptorBacterial
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number32887-01-7
-
Formula Weight325.43
-
Molecular FormulaC15H23N3O3S
-
Purity>98% (HPLC)
-
SolubilityDMSO:Soluble; Water:Insoluble
-
SMILESCC1([C@@H](N2[C@H](S1)[C@@H](C2=O)N=CN3CCCCCC3)C(=O)O)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Thulin E, Sundqvist M, Andersson DI. Amdinocillin (Mecillinam) resistance mutations in clinical isolates and laboratory-selected mutants of Escherichia coli. Antimicrob Agents Chemother. 2015 Mar;59(3):1718-27.
molnova catalog
related products
-
GSK3011724A
GSK3011724A (DG167, GSK3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM).
-
β-Lactamase-IN-1
β-Lactamase-IN-1 is a β-Lactamase inhibitor and targets the infection of Neisseria gonorrhoeae.
-
Ceforanide
Ceforanide is a second-generation cephalosporin antibiotic with bactericidal activity. Ceforanide causes inhibition of bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall.
