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Mecillinam

CAS No. 32887-01-7

Mecillinam( Amdinocillin | AMDINOCILLIN | Coactin | Penicillin HX | Mecillinamum | Hexacillin )

Catalog No. M24265 CAS No. 32887-01-7

Mecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Mecillinam
  • Note
    Research use only, not for human use.
  • Brief Description
    Mecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2).
  • Description
    Mecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2). It is used primarily to treat urinary tract infections and has also been used in the treatment of paratyphoid fever and typhoid.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Mecillinam (Amdinocillin, 400 mg per kg) is effective for the treatment of catheterassociated infections at high dosages (400 mg per kg of body weight/d).Dosage:50, 100, 200, and 400 mg per kg. Administration:Intravenously each day in four divided doses over a 72-h period.Result:High dose of 400 mg/kg exhibited significant activity.
  • Synonyms
    Amdinocillin | AMDINOCILLIN | Coactin | Penicillin HX | Mecillinamum | Hexacillin
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Bacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    32887-01-7
  • Formula Weight
    325.43
  • Molecular Formula
    C15H23N3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble; Water:Insoluble
  • SMILES
    CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)N=CN3CCCCCC3)C(=O)O)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Thulin E, Sundqvist M, Andersson DI. Amdinocillin (Mecillinam) resistance mutations in clinical isolates and laboratory-selected mutants of Escherichia coli. Antimicrob Agents Chemother. 2015 Mar;59(3):1718-27.
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