VAL-083
CAS No. 23261-20-3
VAL-083( Dianhydrogalactitol | Dianhydrodulcitol )
Catalog No. M24063 CAS No. 23261-20-3
VAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 61 | In Stock |
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| 5MG | 69 | In Stock |
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| 10MG | 117 | In Stock |
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| 25MG | 235 | In Stock |
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| 50MG | 338 | In Stock |
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| 100MG | 483 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVAL-083
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NoteResearch use only, not for human use.
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Brief DescriptionVAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
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DescriptionVAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
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In Vitro——
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In Vivo——
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SynonymsDianhydrogalactitol | Dianhydrodulcitol
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA Alkylator
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Research Area——
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Indication——
Chemical Information
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CAS Number23261-20-3
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Formula Weight146.14
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Molecular FormulaC6H10O4
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Purity>98% (HPLC)
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SolubilityDMF :90 mg/mL (615.85 mM);H2O:40 mg/mL (273.71 mM; Need ultrasonic)
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SMILESO[C@H]([C@H](O)[C@@]1([H])OC1)[C@@]2([H])CO2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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HALOFUGINONE LACTATE
HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner with a Ki of 18.3 nM.?Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activityhalofuginone (HF), a widely studied derivative of febrifugine, inhibits the development of T(H)17-driven autoimmunity in a mouse model of multiple sclerosis by activating the amino acid response (AAR) pathway.?HF binds glutamyl-prolyl-tRNA synthetase (EPRS), inhibiting prolyl-tRNA synthetase activity;?this inhibition is reversed by the addition of exogenous proline or EPRS.
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AVG-233
AVG-233 is an orally available RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity that blocks respiratory syncytial virus and SARS-CoV-2 replication.AVG-233 is used in the study of respiratory syncytial virus infections.
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Clevudine
Clevudine is an antiviral drug for the treatment of hepatitis B.
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