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Ceapin-A7

CAS No. 2323027-38-7

Ceapin-A7( —— )

Catalog No. M24061 CAS No. 2323027-38-7

Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 38 In Stock
5MG 37 In Stock
10MG 61 In Stock
25MG 147 In Stock
50MG 245 In Stock
100MG 397 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Ceapin-A7
  • Note
    Research use only, not for human use.
  • Brief Description
    Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings.
  • Description
    Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ATF6α
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2323027-38-7
  • Formula Weight
    470.32
  • Molecular Formula
    C20H12F6N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (212.62 mM; Need ultrasonic)
  • SMILES
    O=C(NC1=CN(CC2=CC=C(C(F)(F)F)C=C2C(F)(F)F)N=C1)C3=NOC(C4=CC=CO4)=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ciara M Gallagher, et al. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. eLife. 2016; 5: e11878.
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