Cart
sales@molnova.com
Pratensein
CAS No. 2284-31-3
Pratensein( —— )
Catalog No. M24038 CAS No. 2284-31-3
Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 376 | In Stock |
|
| 5MG | 376 | In Stock |
|
| 10MG | 534 | In Stock |
|
| 25MG | 845 | In Stock |
|
| 50MG | 1107 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePratensein
-
NoteResearch use only, not for human use.
-
Brief DescriptionPratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
-
DescriptionPratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
-
In Vitro——
-
In VivoPratensein significantly attenuates neuronal degeneration and apoptosis in hippocampus. The over-expression in IL-1β and TNF-α as well as the extensive astrogliosis and microgliosis in hippocampus induced by Aβ1-42 are significantly reduced following administration of Pratensein. Pratensein treatment significantly suppresses the activation of NF-κB in hippocampus. Pratensein is able to increase the levels of synaptophysin and brain-derived neurotrophic factor (BDNF). Pratensein (20 mg/kg; p.o.; once daily for 3 weeks) ameliorates learning and memory deficits in Aβ1-42 rat model of Alzheimer’s disease. Animal Model:Male 10-week old Wistar rats Dosage:20 mg/kg Administration:P.o.; once daily for 3 weeksResult:The spatial learning and memory ability of rats was improved.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2284-31-3
-
Formula Weight300.3
-
Molecular FormulaC16H12O6
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (166.52 mM)
-
SMILESCOC1=C(C=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Protective effect of isoflavones from Trifolium pratense on dopaminergic neurons.Neurosci Res. 2008 Oct;62(2):123-30.
molnova catalog
related products
-
6-Hydroxygenistein
6-Hydroxygenistein is an isoflavonoid compound that can be found in Baptisia hirsuta and serves as a key precursor for the synthesis of various methylated isoflavonoids.
-
Sulfogaiacol
It is an organic compounds with molecular fomular C7H7KO5S.
-
Sauchinone
Sauchinone is a useful adjunctive treatment for bacterial infection. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative stress in vivo and in vitro.
