MARK4 inhibitor 1

CAS No. 2271081-58-2

MARK4 inhibitor 1( —— )

Catalog No. M24033 CAS No. 2271081-58-2

MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 245 In Stock
10MG 356 In Stock
25MG 599 In Stock
50MG 852 In Stock
100MG 1152 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    MARK4 inhibitor 1
  • Note
    Research use only, not for human use.
  • Brief Description
    MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM.
  • Description
    MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM.
  • In Vitro
    Cell Proliferation Assay Cell Line:MCF-7, MDA-MB-435s and HepG2 cells Concentration:0-200 μM Incubation Time:24 and 48 h Result:Decreased the viability of these cells in a concentration dependent manner.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    MARK4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2271081-58-2
  • Formula Weight
    390.4
  • Molecular Formula
    C20H18N6O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O=C(C1=CN(CC2=CC=C(OC)C=C2)N=N1)N\N=C3C4=CC=CC(C)=C4NC\3=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Aneja B, et al. Design and development of Isatin-triazole hydrazones as potential inhibitors of microtubule affinity-regulating kinase 4 for the therapeutic management of cell proliferation and metastasis. Eur J Med Chem. 2019 Feb 1;163:840-852.
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