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AT-007
CAS No. 2170729-29-8
AT-007( —— )
Catalog No. M23983 CAS No. 2170729-29-8
AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 120 | In Stock |
|
| 5MG | 107 | In Stock |
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| 10MG | 180 | In Stock |
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| 25MG | 330 | In Stock |
|
| 50MG | 523 | In Stock |
|
| 100MG | 728 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAT-007
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NoteResearch use only, not for human use.
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Brief DescriptionAT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM).
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DescriptionAT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prevents disease complications in GALT deficiency rats.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetReductase
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RecptorAldose Reductase
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Research Area——
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Indication——
Chemical Information
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CAS Number2170729-29-8
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Formula Weight425.4
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Molecular FormulaC17H10F3N3O3S2
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Purity>98% (HPLC)
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SolubilityDMSO:35.71 mg/mL (83.94 mM; Need ultrasonic)
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SMILESOC(CC(c1cscc11)=NN(Cc2nc(cc(C(F)(F)F)cc3)c3s2)C1=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Maeve Conneighton, et al. Applied Therapeutics Announces Initiation of Phase 1/2 Study of AT-007 in Galactosemia.
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