SB 203186 hydrochloride( —— )

Catalog No. M23932 CAS No. 207572-69-8

SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	31	In Stock
5MG	50	In Stock
10MG	87	In Stock
25MG	178	In Stock
50MG	295	In Stock
100MG	441	In Stock
500MG	972	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

SB 203186 hydrochloride
Note

Research use only, not for human use.
Brief Description

SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist.
Description

SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist.
In Vitro

Pretreatment with SB-203186 (10 μM) enhances the 5-HT-induced contractions of the antral strips.
In Vivo

Intraduodenally administered SB-203186 (0.3-3 mg/kg) to new-born Camborough piglets produced blockade of 5-HT-evoked tachycardia which was maximal after 20 min and lasted for more than 3 h with 0.3 mg/kg.SB-203186 (0.1-3mg/kg, i.v.) surmountably antagonised 5-HT-evoked tachycardia in anaesthetized Yucatan minipigs or new-born Camborough piglets with similar potency.
Synonyms

——
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT4
Research Area

——
Indication

——

Chemical Information

CAS Number

207572-69-8
Formula Weight

308.81
Molecular Formula

C16H20N2O2·HCl
Purity

>98% (HPLC)
Solubility

H2O:100 mM
SMILES

O=C(C1=CNC2=C1C=CC=C2)OCCN3CCCCC3.Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Parker S G , Taylor E M , Hamburger S A , et al. Blockade of human and porcine myocardial 5-HT4 receptors by SB 203186[J]. Naunyn Schmiedebergs Arch Pharmacol, 1995, 353(1):28-35.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks