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DTP3
CAS No. 1809784-29-9
DTP3( —— )
Catalog No. M23824 CAS No. 1809784-29-9
DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 131 | In Stock |
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| 10MG | 226 | In Stock |
|
| 25MG | 362 | In Stock |
|
| 50MG | 600 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDTP3
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NoteResearch use only, not for human use.
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Brief DescriptionDTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.
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DescriptionDTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.
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In Vitro——
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In VivoAnimal Model:6 to 8-week old male NOD/SCID mice (NOD.CB17-Prkdcscid/IcrCrl; Charles River) Dosage:14.5 mg/kg Administration:S.c.; daily; 28 days Result:Had shown a dramatic shrinkage of the tumors.Animal Model:CD1 male mice of 25-30 g Dosage:10 mg/kg (Pharmacokinetic Study) Administration:Intravenous injection Result:Had t1/2 of 1.26 hours, CL of 27.13 ML/min/kg, and Vd of 2.80 L/kg.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorGADD45β/MKK7
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Research Area——
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Indication——
Chemical Information
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CAS Number1809784-29-9
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Formula Weight525.6
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Molecular FormulaC26H35N7O5
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/ml (190.26 mM); Ethanol:100 mg/ml (190.26 mM); Water:100 mg/ml (190.26 mM)
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SMILESCC(=O)N[C@H](CC1=CC=C(C=C1)O)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tornatore L, et al. Cancer Cell. 2014, 26(4), 495-508.
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