Bromo-PEG2-CH2-Boc( —— )

Catalog No. M23819 CAS No. 1807518-63-3

Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Bromo-PEG2-CH2-Boc
Note

Research use only, not for human use.
Brief Description

Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Description

Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

——
Synonyms

——
Pathway

PROTACs
Target

PROTAC
Recptor

PEGs|Alkyl/ether
Research Area

——
Indication

——

Chemical Information

CAS Number

1807518-63-3
Formula Weight

283.16
Molecular Formula

C10H19BrO4
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

CC(C)(C)OC(=O)COCCOCCBr
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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