ICCB-19 HCl(750621-52-4 free base)
CAS No. 1803605-68-6
ICCB-19 HCl(750621-52-4 free base)( —— )
Catalog No. M23816 CAS No. 1803605-68-6
ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 46 | In Stock |
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| 25MG | 92 | In Stock |
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| 50MG | 138 | In Stock |
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| 100MG | 206 | In Stock |
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| 200MG | 306 | In Stock |
|
| 500MG | 485 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameICCB-19 HCl(750621-52-4 free base)
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NoteResearch use only, not for human use.
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Brief DescriptionICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain).
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DescriptionICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorTRADD
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Research Area——
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Indication——
Chemical Information
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CAS Number1803605-68-6
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Formula Weight291.84
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Molecular FormulaC12H22ClN3OS
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESC1CCCC(CC1)NC(=O)CSC2=NCCN2.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Coenzyme FO
Coenzyme FO, a deazaflavin chromophore, is essential as a hydride acceptor/donor in the central methanogenic pathway .
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Laminin (925-933)(TF...
Laminin (925-933) (TFA) is a peptide derived from residues 925-933 of the Laminin B1 chain that binds to the laminin receptor.
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NNMTi
NNMTi? is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM;?50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adipocytes 1-methylnicotinamide level (EC50 = 2.3 μM) without affecting related methyltransferases & enzymes in the NAD+ salvage pathwayNNMTi treatment will rescue age-related deficits in muSC activity to promote superior regeneration post-injury in aging muscle.
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