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Home - Products - Others - Other Targets - ICCB-19 HCl（750621-52-4 free base）

ICCB-19 HCl（750621-52-4 free base）

CAS No. 1803605-68-6

ICCB-19 HCl（750621-52-4 free base）( —— )

Catalog No. M23816 CAS No. 1803605-68-6

ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
5MG 29 In Stock
10MG 46 In Stock
25MG 92 In Stock
50MG 138 In Stock
100MG 206 In Stock
200MG 306 In Stock
500MG 485 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    ICCB-19 HCl（750621-52-4 free base）
  • Note
    Research use only, not for human use.
  • Brief Description
    ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain).
  • Description
    ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TRADD
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1803605-68-6
  • Formula Weight
    291.84
  • Molecular Formula
    C12H22ClN3OS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C1CCCC(CC1)NC(=O)CSC2=NCCN2.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xu D , Zhao H , Jin M , et al. Modulating TRADD to restore cellular homeostasis and inhibit apoptosis[J]. Nature, 2020, 587(7832):1-6.
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