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ICCB-19 HCl（750621-52-4 free base）

CAS No. 1803605-68-6

ICCB-19 HCl（750621-52-4 free base）( —— )

Catalog No. M23816 CAS No. 1803605-68-6

ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	42	In Stock
10MG	72	In Stock
25MG	147	In Stock
50MG	222	In Stock
100MG	332	In Stock
200MG	494	In Stock
500MG	782	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

ICCB-19 HCl（750621-52-4 free base）
Note

Research use only, not for human use.
Brief Description

ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain).
Description

ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

TRADD
Research Area

——
Indication

——

Chemical Information

CAS Number

1803605-68-6
Formula Weight

291.84
Molecular Formula

C12H22ClN3OS
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

C1CCCC(CC1)NC(=O)CSC2=NCCN2.Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Xu D , Zhao H , Jin M , et al. Modulating TRADD to restore cellular homeostasis and inhibit apoptosis[J]. Nature, 2020, 587(7832):1-6.

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