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EGFR/ErbB2 Inhibitor
CAS No. 179248-61-4
EGFR/ErbB2 Inhibitor( —— )
Catalog No. M23804 CAS No. 179248-61-4
EGFR/ErbB2 Inhibitor is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 105 | In Stock |
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| 5MG | 95 | In Stock |
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| 10MG | 143 | In Stock |
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| 25MG | 259 | In Stock |
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| 50MG | 382 | In Stock |
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| 100MG | 554 | In Stock |
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| 200MG | 736 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEGFR/ErbB2 Inhibitor
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NoteResearch use only, not for human use.
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Brief DescriptionEGFR/ErbB2 Inhibitor is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)
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DescriptionEGFR/ErbB2 Inhibitor is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively).
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In VitroEGFR/ErbB-2/ErbB-4 inhibitor-2 (Compound 5) also inhibits c-Src, VEGFR2, c-Fms and with IC50s of 0.30, 2.2, and 14.0 μM, respectively.
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetEGFR
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Recptorc-ErbB2|EGFR|ErbB2
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Research Area——
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Indication——
Chemical Information
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CAS Number179248-61-4
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Formula Weight387.43
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Molecular FormulaC23H21N3O3
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)OCC4=CC=CC=C4)OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Cockerill S , Stubberfield C , Stables J , et al. Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and C-erbB-2.[J]. Bioorganic & Medicinal Chemistry Letters, 2010, 32( 11):no-no.
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