Cart
sales@molnova.com
GR 103691
CAS No. 162408-66-4
GR 103691( —— )
Catalog No. M23720 CAS No. 162408-66-4
GR 103691 is a potent, selective dopamine D3 receptor antagonist (Ki: 0.4 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 57 | In Stock |
|
| 2MG | 33 | In Stock |
|
| 5MG | 53 | In Stock |
|
| 10MG | 93 | In Stock |
|
| 25MG | 187 | In Stock |
|
| 50MG | 299 | In Stock |
|
| 100MG | 477 | In Stock |
|
| 200MG | 677 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGR 103691
-
NoteResearch use only, not for human use.
-
Brief DescriptionGR 103691 is a potent, selective dopamine D3 receptor antagonist (Ki: 0.4 nM).
-
DescriptionGR 103691 is a potent, selective dopamine D3 receptor antagonist (Ki: 0.4 nM). It shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites.
-
In VitroGR 103691 shows marked affinity for serotonin1A (5-HT1A) receptors (Ki of 5.8 nM) and α-1 adrenoceptors (Ki of 12.6 nM).
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetDopamine Receptor
-
RecptorD3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number162408-66-4
-
Formula Weight485.62
-
Molecular FormulaC30H35N3O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESO=C(C1=CC=C(C2=CC=C(C(C)=O)C=C2)C=C1)NCCCCN3CCN(C4=CC=CC=C4OC)CC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Audinot V, et al. A comparative in vitro and in vivo pharmacological characterization of the novel dopamine D3 receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194. J Pharmacol Exp Ther. 1998 Oct;287(1):187-97.
molnova catalog
related products
-
Nomifensine (maleate...
Nomifensine maleate is a selective inhibitor of dopamine uptake, used in adult attention deficit disorder.
-
SKF-83566
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nMSKF-83566 caused a concentration-dependent increase in peak single-pulse evoked extracellular DA concentration, with a maximum increase of 65% in 5 μM SKF-83566.?
-
NMI 8739
NMI 8739 is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release.
