Etripamil

CAS No. 1593673-23-4

Etripamil( MSP-2017 | (-)-MSP-2017 )

Catalog No. M23694 CAS No. 1593673-23-4

Etripamil displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells. Etripamil is an antagonist of short-acting L-type calcium-channel.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 215 In Stock
10MG 340 In Stock
25MG 621 In Stock
50MG 1008 In Stock
100MG 1611 In Stock
500MG 3222 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Etripamil
  • Note
    Research use only, not for human use.
  • Brief Description
    Etripamil displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells. Etripamil is an antagonist of short-acting L-type calcium-channel.
  • Description
    Etripamil displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells. Etripamil is an antagonist of short-acting L-type calcium-channel. It has a rapid onset of action designed for intranasal administration. It is also used to treat Paroxysmal Supraventricular Tachycardia.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MSP-2017 | (-)-MSP-2017
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    L-type calcium channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1593673-23-4
  • Formula Weight
    452.59
  • Molecular Formula
    C27H36N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol : 110 mg/mL (243.05 mM; Need ultrasonic)
  • SMILES
    O=C(OC)C1=CC=CC(CCN(CCC[C@](C2=CC=C(OC)C(OC)=C2)(C#N)C(C)C)C)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Stambler BS, et al. Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm. J Am Coll Cardiol. 2018 Jul 31;72(5):489-497.
molnova catalog
related products
  • alpha-L-Rhamnose

    Addition of the Rhamnose-rich polysaccharide RROP-1 to normal human dermal fibroblasts (NHDFs) and human endothelial cells produced a dose-dependent stimulation of the calcium-signaling pathway inducing fast and transient increases in Ca2 influx and intracellular free Ca2 level.

  • Ziconotide Acetate

    Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.

  • DHBP dibromide

    DHBP dibromide is calcium release and a muscle relaxant inhibitor.