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Licofelone
CAS No. 156897-06-2
Licofelone( ML-3000 )
Catalog No. M23680 CAS No. 156897-06-2
Licofelone is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
|
| 5MG | 37 | In Stock |
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| 10MG | 61 | In Stock |
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| 25MG | 122 | In Stock |
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| 50MG | 183 | In Stock |
|
| 100MG | 272 | In Stock |
|
| 200MG | 406 | In Stock |
|
| 500MG | 644 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLicofelone
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NoteResearch use only, not for human use.
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Brief DescriptionLicofelone is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory.
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DescriptionLicofelone is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory. Inhibition of 5-LOX may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase).
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In Vitro——
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In Vivo——
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SynonymsML-3000
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PathwayChromatin/Epigenetic
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TargetCOX
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Recptor5-LOX|COX
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Research Area——
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Indication——
Chemical Information
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CAS Number156897-06-2
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Formula Weight379.88
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Molecular FormulaC23H22ClNO2
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Purity>98% (HPLC)
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SolubilityDMSO:25 mg/mL (65.81 mM; Need ultrasonic)
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SMILESCC(C)(C1)Cn(c(CC(O)=O)c2-c(cc3)ccc3Cl)c1c2-c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tavolari S, et al. Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade. Carcinogenesis. 2008 Feb;29(2):371-80.
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