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Homo-VK-II-36

CAS No. 1479049-35-8

Homo-VK-II-36( Homo VK II 36 | HomoVKII36 | Homo-V-II-36 )

Catalog No. M23634 CAS No. 1479049-35-8

Homo-VK-II-36 is a carvedilol analogue that acts by inhibiting store- overload-induced calcium release through the RyR2 channel.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 158 In Stock
5MG 155 In Stock
10MG 250 In Stock
25MG 432 In Stock
50MG 616 In Stock
100MG 892 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Homo-VK-II-36
  • Note
    Research use only, not for human use.
  • Brief Description
    Homo-VK-II-36 is a carvedilol analogue that acts by inhibiting store- overload-induced calcium release through the RyR2 channel.
  • Description
    Homo-VK-II-36 is a carvedilol analogue that acts by inhibiting store- overload-induced calcium release through the RyR2 channel.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Homo VK II 36 | HomoVKII36 | Homo-V-II-36
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    RyR2 channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1479049-35-8
  • Formula Weight
    460.53
  • Molecular Formula
    C27H28N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    COC1=CC=CC=C1OCCN2CC(OCC2=O)CCOC3=CC=CC4=C3C5=CC=CC=C5N4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang JZ, McLay JC, Jones PP. The arrhythmogenic human HRC point mutation S96A leads to spontaneous Ca(2+) release due to an impaired ability to buffer store Ca(2+). J Mol Cell Cardiol. 2014 Sep;74:22-31. doi: 10.1016/j.yjmcc.2014.04.019. Epub 2014 May 5. PubMed PMID: 24805197.
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