Homo-VK-II-36( Homo VK II 36 | HomoVKII36 | Homo-V-II-36 )

Catalog No. M23634 CAS No. 1479049-35-8

Homo-VK-II-36 is a carvedilol analogue that acts by inhibiting store- overload-induced calcium release through the RyR2 channel.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	158	In Stock
5MG	155	In Stock
10MG	250	In Stock
25MG	432	In Stock
50MG	616	In Stock
100MG	892	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Homo-VK-II-36
Note

Research use only, not for human use.
Brief Description

Homo-VK-II-36 is a carvedilol analogue that acts by inhibiting store- overload-induced calcium release through the RyR2 channel.
Description

Homo-VK-II-36 is a carvedilol analogue that acts by inhibiting store- overload-induced calcium release through the RyR2 channel.
In Vitro

——
In Vivo

——
Synonyms

Homo VK II 36 | HomoVKII36 | Homo-V-II-36
Pathway

Others
Target

Other Targets
Recptor

RyR2 channel
Research Area

——
Indication

——

Chemical Information

CAS Number

1479049-35-8
Formula Weight

460.53
Molecular Formula

C27H28N2O5
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

COC1=CC=CC=C1OCCN2CC(OCC2=O)CCOC3=CC=CC4=C3C5=CC=CC=C5N4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Zhang JZ, McLay JC, Jones PP. The arrhythmogenic human HRC point mutation S96A leads to spontaneous Ca(2+) release due to an impaired ability to buffer store Ca(2+). J Mol Cell Cardiol. 2014 Sep;74:22-31. doi: 10.1016/j.yjmcc.2014.04.019. Epub 2014 May 5. PubMed PMID: 24805197.

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