Cart
sales@molnova.com
Homo-VK-II-36
CAS No. 1479049-35-8
Homo-VK-II-36( Homo VK II 36 | HomoVKII36 | Homo-V-II-36 )
Catalog No. M23634 CAS No. 1479049-35-8
Homo-VK-II-36 is a carvedilol analogue that acts by inhibiting store- overload-induced calcium release through the RyR2 channel.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 158 | In Stock |
|
| 5MG | 155 | In Stock |
|
| 10MG | 250 | In Stock |
|
| 25MG | 432 | In Stock |
|
| 50MG | 616 | In Stock |
|
| 100MG | 892 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameHomo-VK-II-36
-
NoteResearch use only, not for human use.
-
Brief DescriptionHomo-VK-II-36 is a carvedilol analogue that acts by inhibiting store- overload-induced calcium release through the RyR2 channel.
-
DescriptionHomo-VK-II-36 is a carvedilol analogue that acts by inhibiting store- overload-induced calcium release through the RyR2 channel.
-
In Vitro——
-
In Vivo——
-
SynonymsHomo VK II 36 | HomoVKII36 | Homo-V-II-36
-
PathwayOthers
-
TargetOther Targets
-
RecptorRyR2 channel
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1479049-35-8
-
Formula Weight460.53
-
Molecular FormulaC27H28N2O5
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESCOC1=CC=CC=C1OCCN2CC(OCC2=O)CCOC3=CC=CC4=C3C5=CC=CC=C5N4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Zhang JZ, McLay JC, Jones PP. The arrhythmogenic human HRC point mutation S96A leads to spontaneous Ca(2+) release due to an impaired ability to buffer store Ca(2+). J Mol Cell Cardiol. 2014 Sep;74:22-31. doi: 10.1016/j.yjmcc.2014.04.019. Epub 2014 May 5. PubMed PMID: 24805197.
molnova catalog
related products
-
Carpachromene
Carpachromene could be a potential anti-inflammatory agent, it blocks protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in LPS-stimulated macrophages.Carpachromene shows significant α-glucosidase inhibitory activity.
-
Fibrinogen Related P...
Fibrinogen γ-chain (397-411), a esidues 397-411 of the γ chain of fibrinogen, is a site recognizing the platelet receptor, which is distinct from the site(s) involved in polymerization of fibrin monomers.
-
Albanin A
Albanin A, a flavonoid, suppresses glutamate release by decreasing Ca2+/calmodulin/adenylate Cyclase 1 (AC1) activation in synaptosomes and exerts neuroprotective effect in vivo. Albanin A has anti-inflflammatory activity.
