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Cnidicin
CAS No. 14348-21-1
Cnidicin( —— )
Catalog No. M23598 CAS No. 14348-21-1
Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 5MG | 320 | In Stock |
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| 10MG | 447 | In Stock |
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| 50MG | 887 | In Stock |
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Biological Information
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Product NameCnidicin
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NoteResearch use only, not for human use.
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Brief DescriptionCnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM).
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DescriptionCnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the proliferation of cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon) in vitro .
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In VitroCnidicin shows a significant inhibition upon the release of beta-hexosaminidase from the cultured RBL-2H3 cells in a dose dependent manner (IC50= 25 μM) and upon the nitric oxide production from the activated RAW264.7 cells (IC50=7.5 μM).
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetNOS
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RecptorNO Synthase|NOS
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Research Area——
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Indication——
Chemical Information
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CAS Number14348-21-1
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Formula Weight354.4
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Molecular FormulaC21H22O5
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCC(=CCOC1=C2C=COC2=C(C3=C1C=CC(=O)O3)OCC=C(C)C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Antiproliferative effect of furanocoumarins from the root of Angelica dahurica on cultured human tumor cell lines.Phytother Res. 2007 Mar;21(3):288-90.
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