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DBCO-PEG4-NHS ester
CAS No. 1427004-19-0
DBCO-PEG4-NHS ester( —— )
Catalog No. M23584 CAS No. 1427004-19-0
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 49 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 48 | In Stock |
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| 25MG | 85 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDBCO-PEG4-NHS ester
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NoteResearch use only, not for human use.
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Brief DescriptionDBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DescriptionDBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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RecptorPEGs
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Research Area——
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Indication——
Chemical Information
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CAS Number1427004-19-0
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Formula Weight649.69
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Molecular FormulaC34H39N3O10
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Purity>98% (HPLC)
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SolubilityDMSO:79 mg/mL?(121.59 mM;?Need ultrasonic)
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SMILESO=C(CCC(N(C1)c(cccc2)c2C#Cc2c1cccc2)=O)NCCOCCOCCOCCOCCC(ON(C(CC1)=O)C1=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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