Cart
sales@molnova.com
Home - Products - PROTACs - PROTAC - DBCO-PEG4-NHS ester

DBCO-PEG4-NHS ester

CAS No. 1427004-19-0

DBCO-PEG4-NHS ester( —— )

Catalog No. M23584 CAS No. 1427004-19-0

DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 132 In Stock
10MG 222 In Stock
25MG 376 In Stock
50MG 536 In Stock
100MG 777 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    DBCO-PEG4-NHS ester
  • Note
    Research use only, not for human use.
  • Brief Description
    DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    PEGs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1427004-19-0
  • Formula Weight
    649.69
  • Molecular Formula
    C34H39N3O10
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:79 mg/mL?(121.59 mM;?Need ultrasonic)
  • SMILES
    O=C(CCC(N(C1)c(cccc2)c2C#Cc2c1cccc2)=O)NCCOCCOCCOCCOCCC(ON(C(CC1)=O)C1=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Biotin-PEG3-acid

    Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule.

  • Azido-PEG1-azide

    Azido-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

  • CCT-367766

    CCT-367766 (CCT367766) is a novel heterobifunctional PROTAC that binds and degrades the putative transcription factor regulator Pirin in cells.

Sign In Join Free