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Vodobatinib

CAS No. 1388803-90-4

Vodobatinib( K-0706 )

Catalog No. M23547 CAS No. 1388803-90-4

Vodobatinib is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.

Purity : >98% (HPLC)

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Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	75	In Stock
5MG	68	In Stock
10MG	112	In Stock
25MG	212	In Stock
50MG	333	In Stock
100MG	517	In Stock
200MG	Get Quote	In Stock
500MG	1249	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Vodobatinib
Note

Research use only, not for human use.
Brief Description

Vodobatinib is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.
Description

Vodobatinib is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.
In Vitro

In Ba/F3 cells expressing BCR-ABL1, BCR-ABL1L248V, BCR-ABL1Y253H, or BCR-ABL1E255V, Vodobatinib (K0706; 0-2000 nM) treatment shows potent inhibition of BCR-ABL1 tyrosine autophosphorylation.
In Vivo

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Synonyms

K-0706
Pathway

Angiogenesis
Target

Bcr-Abl
Recptor

BCR-ABL1
Research Area

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Indication

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Chemical Information

CAS Number

1388803-90-4
Formula Weight

453.92
Molecular Formula

C27H20ClN3O2
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

CC1=C(C(=CC=C1)Cl)C(=O)NNC(=O)C2=CC(=C(C=C2)C)C#CC3=CC4=CC=CC=C4N=C3
Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

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