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4-P-PDOT
CAS No. 134865-74-0
4-P-PDOT( 4-phenyl-2- propionamidotetralin )
Catalog No. M23510 CAS No. 134865-74-0
4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 54 | In Stock |
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| 2MG | 31 | In Stock |
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| 5MG | 49 | In Stock |
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| 10MG | 85 | In Stock |
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| 25MG | 177 | In Stock |
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| 50MG | 276 | In Stock |
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| 100MG | 481 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name4-P-PDOT
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NoteResearch use only, not for human use.
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Brief Description4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
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Description4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
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In VitroCell Viability Assay Cell Line:HT-29 and HeLa cells.Concentration:50 μM Incubation Time:30 min Result:Produced a negligible effect on cell viability induced by melatonin.
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In VivoAnimal Model:Klotho mutant mice treatment with Melatonin Dosage:0.5 mg/kg or 1.0 mg/kg Administration:Intravenous injection Result:Significantly reversed antioxidant effects mediated by Melatonin. Significantly reversed the changes in the levels of these GSH-related parameters. Significantly reversed the memory function of Melatonin-treated klotho mutant mice.
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Synonyms4-phenyl-2- propionamidotetralin
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PathwayOthers
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TargetOther Targets
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RecptorMT2 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number134865-74-0
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Formula Weight279.38
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Molecular FormulaC19H21NO
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Purity>98% (HPLC)
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SolubilityDMSO:41.67 mg/mL (149.15 mM; Need ultrasonic)
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SMILESCCC(=O)NC1CC(C2=CC=CC=C2C1)C3=CC=CC=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dubocovich ML. Melatonin receptors: are there multiple subtypes? Trends Pharmacol Sci. 1995 Feb;16(2):50-6.
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