BIA( —— )

Catalog No. M23500 CAS No. 134271-74-2

BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	48	In Stock
5MG	33	In Stock
10MG	55	In Stock
25MG	112	In Stock
50MG	178	In Stock
100MG	267	In Stock
200MG	370	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

BIA
Note

Research use only, not for human use.
Brief Description

BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.
Description

BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.
In Vitro

CDC25B-IN-2 (compound 27; 20 μg/mL) has cdc25B enzyme inhibitory activities 16.11% in vitro.
In Vivo

——
Synonyms

——
Pathway

PI3K/Akt/mTOR signaling
Target

mTOR
Recptor

TMBIM6
Research Area

——
Indication

——

Chemical Information

CAS Number

134271-74-2
Formula Weight

268.27
Molecular Formula

C15H12N2O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (931.90 mM)
SMILES

O=C(C1=CC=CC=C1N)/C=C/C2=CC=CC([N+]([O-])=O)=C2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Kim H K , Bhattarai K R , Junjappa R P , et al. TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation[J]. Nature Communications, 2020, 11(1).

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