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CFI-400945
CAS No. 1338806-73-7
CFI-400945( —— )
Catalog No. M23495 CAS No. 1338806-73-7
CFI-400945 is an potent, selective and orally active inhibitor of polo-like kinase 4(PLK4; Ki value of 0.26 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 93 | In Stock |
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| 5MG | 84 | In Stock |
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| 10MG | 136 | In Stock |
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| 25MG | 280 | In Stock |
|
| 50MG | 477 | In Stock |
|
| 100MG | 761 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCFI-400945
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NoteResearch use only, not for human use.
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Brief DescriptionCFI-400945 is an potent, selective and orally active inhibitor of polo-like kinase 4(PLK4; Ki value of 0.26 nM).
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DescriptionCFI-400945 is an potent, selective and orally active inhibitor of polo-like kinase 4(PLK4; Ki value of 0.26 nM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPLK
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RecptorPLK4
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Research Area——
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Indication——
Chemical Information
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CAS Number1338806-73-7
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Formula Weight534.65
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Molecular FormulaC33H34N4O3
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (187.04 mM;warmed with 50oC water bath);Ethanol:100 mg/mL (187.04 mM);Water:Insoluble
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SMILESC[C@@H]1CN(C[C@@H](O1)C)CC2=CC=C(C=C2)/C=C/C3=NNC4=C3C=CC(=C4)[C@@H]5C[C@]56C7=C(C=CC(=C7)OC)NC6=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Mason J , Lin D C , Wei X , et al. Functional Characterization of CFI-400945, a Polo-like Kinase 4 Inhibitor, as a Potential Anticancer Agent[J]. Cancer Cell, 2014, 26(2).
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