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Mito-TEMPO
CAS No. 1334850-99-5
Mito-TEMPO( —— )
Catalog No. M23487 CAS No. 1334850-99-5
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO with superoxide and alkyl radical scavenging properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
|
| 5MG | 48 | In Stock |
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| 10MG | 85 | In Stock |
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| 25MG | 169 | In Stock |
|
| 50MG | 319 | In Stock |
|
| 100MG | 531 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMito-TEMPO
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NoteResearch use only, not for human use.
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Brief DescriptionMito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO with superoxide and alkyl radical scavenging properties.
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DescriptionMito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO with superoxide and alkyl radical scavenging properties.(In Vivo):Mito-TEMPO (MT) greatly attenuates the increase in ALT activities and reduces the areas of necrosis at both time points, indicating that the protection by Mito-TEMPO is sustained until at least 24 h post-APAP. Mito-Tempo could induce secondary apoptosis in the late phase of APAP hepatotoxicity. Mito-Tempo induces secondary apoptosis after APAP overdose by inhibition of RIP3.
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In Vitro——
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In VivoMito-TEMPO (MT) greatly attenuates the increase in ALT activities and reduces the areas of necrosis at both time points, indicating that the protection by Mito-TEMPO is sustained until at least 24 h post-APAP. Mito-Tempo could induce secondary apoptosis in the late phase of APAP hepatotoxicity. Mito-Tempo induces secondary apoptosis after APAP overdose by inhibition of RIP3.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorMitochondrial Metabolism
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Research Area——
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Indication——
Chemical Information
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CAS Number1334850-99-5
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Formula Weight510.03
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Molecular FormulaC29H35ClN2O2P
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (245.08 mM; Need ultrasonic);H2O:60 mg/mL (117.64 mM; Need ultrasonic)
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SMILES[O]N1C(C)(C)CC(NC(C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)=O)CC1(C)C.[Cl-]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Du K, et al. Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity. Arch Toxicol. 2018 Oct 15.
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