Cart
sales@molnova.com
Vamorolone
CAS No. 13209-41-1
Vamorolone( VBP15 )
Catalog No. M23477 CAS No. 13209-41-1
Vamorolone is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 75 | In Stock |
|
| 2MG | 42 | In Stock |
|
| 5MG | 68 | In Stock |
|
| 10MG | 107 | In Stock |
|
| 25MG | 188 | In Stock |
|
| 50MG | 291 | In Stock |
|
| 100MG | 435 | In Stock |
|
| 200MG | 626 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVamorolone
-
NoteResearch use only, not for human use.
-
Brief DescriptionVamorolone is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer.
-
DescriptionVamorolone is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects. Vamorolone displays effective NF-κB inhibition and substantially decreases hormonal effects.
-
In Vitro——
-
In VivoAnimal Model:C57BL/6 mice (experimental autoimmune encephalomyelitis)Dosage:30 mg/kg Administration:Orally; daily for 20 days (starting one day prior to MOG 33-55 peptide immunization and continuing)Result:Reduced CNS inflammation in murine experimental autoimmune encephalomyelitis.
-
SynonymsVBP15
-
PathwayApoptosis
-
TargetNF-κB
-
RecptorGlucocorticoid Receptor|Mineralocorticoid Receptor|NF-κB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number13209-41-1
-
Formula Weight356.46
-
Molecular FormulaC22H28O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:62.5 mg/mL (175.34 mM; Need ultrasonic)
-
SMILESC[C@H](C[C@@H]([C@@H]1CC2)[C@]3(C)CC=C1[C@@](C)(C=C1)C2=CC1=O)[C@@]3(C(CO)=O)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Heier CR, et al. VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects. EMBO Mol Med. 2013 Oct;5(10):1569-85.
molnova catalog
related products
-
Pyrrolidinedithiocar...
Pyrrolidinedithiocarbamate ammonium is a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction.
-
Andrographolide
Andrographolide(Andrographis) is an irreversible antagonist of NF-κB and prevents in vitro T cell activation.
-
Ramosetron
Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron.
