Cart
sales@molnova.com
Sephin1
CAS No. 13098-73-2
Sephin1( NSC 65390 | IFB-088 )
Catalog No. M23468 CAS No. 13098-73-2
Sephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 59 | In Stock |
|
| 50MG | 90 | In Stock |
|
| 100MG | 136 | In Stock |
|
| 200MG | 203 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSephin1
-
NoteResearch use only, not for human use.
-
Brief DescriptionSephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α
-
DescriptionSephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α.
-
In Vitro——
-
In Vivo——
-
SynonymsNSC 65390 | IFB-088
-
PathwayMetabolic Enzyme/Protease
-
TargetPhospholipase
-
Recptorphosphatase PPP1R15A
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number13098-73-2
-
Formula Weight196.64
-
Molecular FormulaC8H9ClN4
-
Purity>98% (HPLC)
-
SolubilityDMSO:7mg/ml(35.60mM);H2O:insoluble
-
SMILESNC(N)=NN=Cc(cccc1)c1Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Ruiz A , Zuazo J , Ortiz-Sanz C , et al. Sephin1 Protects Neurons against Excitotoxicity Independently of the Integrated Stress Response[J]. International Journal of Molecular Sciences, 2020, 21(17):6088.
molnova catalog
related products
-
Melittin TFA(20449-7...
Melittin TFA is a small protein containing 26 amino acid residues, is the principal toxic component of bee venom. Melittin is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2.Melittin, an immunologically related PLA2 stimulating peptide from bee venom, increases the activity of the high molecular weight enzyme.
-
Lp-PLA2-IN-1
Lp-PLA2 -IN-1 suppresses Lp-PLA2 activity processes for their preparation.
-
VU0359595
VU0359595 (ML-270) is a potent and selective pharmacological phospholipase D1 (PLD1) inhibitor with an IC50 of 3.7 nM. VU0359595 is >1700-fold selective for PLD1 over PLD2 (IC50 of 6.4 μM).
