Sephin1

CAS No. 13098-73-2

Sephin1( NSC 65390 | IFB-088 )

Catalog No. M23468 CAS No. 13098-73-2

Sephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
10MG 33 In Stock
25MG 57 In Stock
50MG 83 In Stock
100MG 126 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Sephin1
  • Note
    Research use only, not for human use.
  • Brief Description
    Sephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α
  • Description
    Sephin1 is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC 65390 | IFB-088
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phospholipase
  • Recptor
    phosphatase PPP1R15A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    13098-73-2
  • Formula Weight
    196.64
  • Molecular Formula
    C8H9ClN4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:7mg/ml(35.60mM);H2O:insoluble
  • SMILES
    NC(N)=NN=Cc(cccc1)c1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ruiz A , Zuazo J , Ortiz-Sanz C , et al. Sephin1 Protects Neurons against Excitotoxicity Independently of the Integrated Stress Response[J]. International Journal of Molecular Sciences, 2020, 21(17):6088.
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