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B355252

CAS No. 1261576-81-1

B355252( —— )

Catalog No. M23435 CAS No. 1261576-81-1

B355252 protects against cell death caused by glutamate-evoked oxidative stress.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 81 In Stock
5MG 61 In Stock
10MG 87 In Stock
25MG 154 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    B355252
  • Note
    Research use only, not for human use.
  • Brief Description
    B355252 protects against cell death caused by glutamate-evoked oxidative stress.
  • Description
    B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.
  • In Vitro
    ——
  • In Vivo
    B-355252 (0.125 mg/kg; ip; daily; 3 days) significantly attenuates the infarct volume and protects post-stroke neuronal loss in adult male Sprague–Dawley rats with cerebral ischemia.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1261576-81-1
  • Formula Weight
    514.06
  • Molecular Formula
    C25H24ClN3O3S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C1CN(CCN1)C2=CC(=CC=C2)OC3=C(C=C(S3)S(=O)(=O)NCC4=CC=CC5=CC=CC=C54)Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chimeh U , Zimmerman M A , Gilyazova N , et al. B355252, A Novel Small Molecule, Confers Neuroprotection Against Cobalt Chloride Toxicity In Mouse Hippocampal Cells Through Altering Mitochondrial Dynamics And Limiting Autophagy Induction[J]. International Journal of Medical Sciences, 2018, 15(12):1384-1396.
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