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CID44216842

CAS No. 1222513-26-9

CID44216842( KUC103479N-02 )

Catalog No. M23391 CAS No. 1222513-26-9

CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	50	In Stock
2MG	29	In Stock
5MG	46	In Stock
10MG	78	In Stock
25MG	162	In Stock
50MG	252	In Stock
100MG	370	In Stock
200MG	528	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

CID44216842
Note

Research use only, not for human use.
Brief Description

CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor.
Description

CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.
In Vitro

CID44216842 inhibits GTP binding to both Cdc42 and its mutant in a dose-dependent manner. The inhibition is specific toward Cdc42 with no effects on other GTPases including Rac and Rho in the same family.
In Vivo

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Synonyms

KUC103479N-02
Pathway

Angiogenesis
Target

CDK
Recptor

Cdc42
Research Area

——
Indication

——

Chemical Information

CAS Number

1222513-26-9
Formula Weight

486.38
Molecular Formula

C22H20BrN3O3S
Purity

>98% (HPLC)
Solubility

DMSO:250 mg/mL?(514.00 mM;?Need ultrasonic)
SMILES

O=S(C1=CC=C(N2N=C(C3=CC=CC(OC)=C3)CC2C4=CC=C(Br)C=C4)C=C1)(N)=O
Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Lin Hong, et al. Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe. J Biol Chem. 2013 Mar 22;288(12):8531-43.

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