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NITD-2
CAS No. 1197896-79-9
NITD-2( —— )
Catalog No. M23369 CAS No. 1197896-79-9
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 205 | In Stock |
|
| 10MG | 312 | In Stock |
|
| 25MG | 530 | In Stock |
|
| 50MG | 758 | In Stock |
|
| 100MG | 1044 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNITD-2
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NoteResearch use only, not for human use.
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Brief DescriptionNITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation.
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DescriptionNITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in humans. Neither vaccine nor antiviral therapy is currently available for DENV.
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In VitroNITD-2 inhibits de novo RNA synthesis.NITD-2 exhibited no antiviral activity in cell culture resulted from the poor cell penetratration.
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorRNA Synthesis
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Research Area——
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Indication——
Chemical Information
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CAS Number1197896-79-9
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Formula Weight433.48
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Molecular FormulaC23H19N3O4S
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESO=C(O)C1=CC=CC=C1NS(=O)(C2=CC=CC(C3=CN(CC4=CC=CC=C4)N=C3)=C2)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Pornwaratt Niyomrattanakit, et al. Inhibition of dengue virus polymerase by blocking of the RNA tunnel. J Virol. 2010 Jun;84(11):5678-86.
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