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Home - Products - Cell Cycle/DNA Damage - DNA/RNA Synthesis - NITD-2

NITD-2

CAS No. 1197896-79-9

NITD-2( —— )

Catalog No. M23369 CAS No. 1197896-79-9

NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 188 In Stock
5MG 170 In Stock
10MG 275 In Stock
25MG 471 In Stock
50MG 641 In Stock
100MG 923 In Stock
200MG 1237 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    NITD-2
  • Note
    Research use only, not for human use.
  • Brief Description
    NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation.
  • Description
    NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in humans. Neither vaccine nor antiviral therapy is currently available for DENV.
  • In Vitro
    NITD-2 inhibits de novo RNA synthesis.NITD-2 exhibited no antiviral activity in cell culture resulted from the poor cell penetratration.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1197896-79-9
  • Formula Weight
    433.48
  • Molecular Formula
    C23H19N3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O=C(O)C1=CC=CC=C1NS(=O)(C2=CC=CC(C3=CN(CC4=CC=CC=C4)N=C3)=C2)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Pornwaratt Niyomrattanakit, et al. Inhibition of dengue virus polymerase by blocking of the RNA tunnel. J Virol. 2010 Jun;84(11):5678-86.
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