Hydroxychloroquine( —— )

Catalog No. M23351 CAS No. 118-42-3

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Hydroxychloroquine
Note

Research use only, not for human use.
Brief Description

Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9.
Description

Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a medication used to prevent and treat malaria, and it's also being studied as an experimental treatment for COVID-19.
In Vitro

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In Vivo

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Synonyms

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Pathway

Immunology/Inflammation
Target

TLR
Recptor

TLR7/9
Research Area

——
Indication

——

CAS Number

118-42-3
Formula Weight

335.87
Molecular Formula

C18H26ClN3O
Purity

>98% (HPLC)
Solubility

1M HCl : 99 mg/mL (294.75 mM; adjust pH to 2 with HCl); H2O : 1.65 mg/mL (4.91 mM; ultrasonic and warming and heat to 60°C); DMSO : < 1 mg/mL (insoluble or slightly soluble)
SMILES

CCN(CCCC(C)Nc1c(ccc(Cl)c2)c2ncc1)CCO
Chemical Name

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1.Ponticelli C, Moroni G. Hydroxychloroquine in systemic lupus erythematosus (SLE). Expert Opin Drug Saf. 2017 Mar;16(3):411-419.

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