Cart
sales@molnova.com
A 1120
CAS No. 1152782-19-8
A 1120( —— )
Catalog No. M23331 CAS No. 1152782-19-8
A 1120 is a nonretinoid retinol-binding protein 4 (RBP4) antagonist (Ki: 8.3 nM), which disrupts the interaction between RBP4 and its binding partner transthyretin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 93 | In Stock |
|
| 2MG | 51 | In Stock |
|
| 5MG | 85 | In Stock |
|
| 10MG | 140 | In Stock |
|
| 25MG | 282 | In Stock |
|
| 50MG | 445 | In Stock |
|
| 100MG | 639 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1293 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameA 1120
-
NoteResearch use only, not for human use.
-
Brief DescriptionA 1120 is a nonretinoid retinol-binding protein 4 (RBP4) antagonist (Ki: 8.3 nM), which disrupts the interaction between RBP4 and its binding partner transthyretin.
-
DescriptionA 1120 is a nonretinoid retinol-binding protein 4 (RBP4) antagonist (Ki: 8.3 nM), which disrupts the interaction between RBP4 and its binding partner transthyretin.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorRBP4
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1152782-19-8
-
Formula Weight392.37
-
Molecular FormulaC20H19F3N2O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:95 mg/mL?(242.12 mM;?Need ultrasonic)
-
SMILESOC(c(cccc1)c1NC(N(CC1)CCC1c1c(C(F)(F)F)cccc1)=O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Motani A, et al. Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo. J Biol Chem. 2009 Mar 20;284(12):7673-80.
molnova catalog
related products
-
[D-Arg0,Hyp3,D-Phe7,...
[D-Arg0,Hyp3,D-Phe7,Leu8]-Bradykinin
-
Iopamidol
Iopamidol is a nonionic, low-osmolar iodinated contrast agent.
-
Fz7-21
Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100?nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50?nM).
