Tunicamycin

CAS No. 11089-65-9

Tunicamycin( —— )

Catalog No. M23310 CAS No. 11089-65-9

Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 88 In Stock
5MG 145 In Stock
10MG 259 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Tunicamycin
  • Note
    Research use only, not for human use.
  • Brief Description
    Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT).
  • Description
    Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity.
  • In Vitro
    Western Blot Analysis Cell Line:CD44+/CD24- and original MCF7 cells Concentration:2 μg/mL Incubation Time:24 hours Result:Increased level of spliced XBP-1, ATF6 nuclear translocation and CHOP protein expression are detected in CD44+/CD24- and original MCF7 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    Bacterial|antiFungal|Influenza virus|Antibiotic
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    11089-65-9
  • Formula Weight
    844.94(n=10)
  • Molecular Formula
    C39H64N4O16
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:40 mg/mL (Need ultrasonic)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hsu JL, et al. Tunicamycin induces resistance to camptothecin and etoposide in human hepatocellular carcinoma cells: role of cell-cycle arrest and GRP78. Naunyn Schmiedebergs Arch Pharmacol. 2009 Nov;380(5):373-82.
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