Tunicamycin

CAS No. 11089-65-9

Tunicamycin( —— )

Catalog No. M23310 CAS No. 11089-65-9

Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 286 In Stock
10MG 484 In Stock
25MG 771 In Stock
100MG Get Quote In Stock
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Biological Information

  • Product Name
    Tunicamycin
  • Note
    Research use only, not for human use.
  • Brief Description
    Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT).
  • Description
    Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity.
  • In Vitro
    Western Blot Analysis Cell Line:CD44+/CD24- and original MCF7 cells Concentration:2 μg/mL Incubation Time:24 hours Result:Increased level of spliced XBP-1, ATF6 nuclear translocation and CHOP protein expression are detected in CD44+/CD24- and original MCF7 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    Bacterial|antiFungal|Influenza virus|Antibiotic
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    11089-65-9
  • Formula Weight
    844.94(n=10)
  • Molecular Formula
    C39H64N4O16
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:40 mg/mL (Need ultrasonic)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hsu JL, et al. Tunicamycin induces resistance to camptothecin and etoposide in human hepatocellular carcinoma cells: role of cell-cycle arrest and GRP78. Naunyn Schmiedebergs Arch Pharmacol. 2009 Nov;380(5):373-82.
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