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Evenamide

CAS No. 1092977-61-1

Evenamide( NW-3509 )

Catalog No. M23295 CAS No. 1092977-61-1

Evenamide is a sodium channel blocker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 85 In Stock
5MG 77 In Stock
10MG 123 In Stock
25MG 250 In Stock
50MG 390 In Stock
100MG 631 In Stock
200MG 879 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Evenamide
  • Note
    Research use only, not for human use.
  • Brief Description
    Evenamide is a sodium channel blocker.
  • Description
    Evenamide is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.
  • In Vitro
    Evenamide selectively blocks voltage-gated sodium channels (VGSCs) in a voltage-and use-dependent manner (Ki=0.4 μM) and modulates sustained repetitive firing without inducing impairment of the normal neuronal excitability. Evenamide does not bind, inhibit or interact with over 130 receptors, enzymes, or transporters.
  • In Vivo
    Evenamide is active in a wide range of psychiatric animal models in monotherapy and addon to antipsychotics. Evenamide is effective in attenuating the social interaction deficit in Cl 395 (PCP)-impaired rats (MED=1 mg/kg po).
  • Synonyms
    NW-3509
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Sodium channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1092977-61-1
  • Formula Weight
    278.39
  • Molecular Formula
    C16H26N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:290 mg/mL (1041.70 mM; Need ultrasonic)
  • SMILES
    CCCCOc1cccc(CCNCC(N(C)C)=O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Valentina Zuliani, et al. Advances in Design and Development of Sodium Channel Blockers. Ion Channels and Their Inhibitors pp 79-115.
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