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Garcinone D

CAS No. 107390-08-9

Garcinone D( —— )

Catalog No. M23282 CAS No. 107390-08-9

Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Garcinone D
Note

Research use only, not for human use.
Brief Description

Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml.
Description

Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 activation with IC50 values of 3.2 microM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Immunology/Inflammation
Target

ROS
Recptor

Keap1-Nrf2|Reactive Oxygen Species|STAT3
Research Area

——
Indication

——

Chemical Information

CAS Number

107390-08-9
Formula Weight

428.48
Molecular Formula

C24H28O7
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (116.69 mM)
SMILES

CC(C)(O)CCC1=C(OC)C(O)=CC(OC2=CC(O)=C(C/C=C(C)/C)C(O)=C23)=C1C3=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Garcinia mangostana: a source of potential anti-cancer lead compounds against CEM-SS cell line.J Asian Nat Prod Res. 2008 May-Jun;10(5-6):475-9.

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