ELOVL6-IN-2

CAS No. 1067647-43-1

ELOVL6-IN-2( —— )

Catalog No. M23274 CAS No. 1067647-43-1

ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 41 In Stock
5MG 31 In Stock
10MG 55 In Stock
25MG 112 In Stock
50MG 207 In Stock
100MG 309 In Stock
200MG 442 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ELOVL6-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.
  • Description
    ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male C57BL/6J mice Dosage:0.1~1mg/kg Administration:P.o Result:Potently and dose-proportionally suppressed the elongation index in the liver.Animal Model:Male C57BL/6J mice Dosage:10 mg/kg Administration:P.o Result:Demonstrated highly liver penetrable.Animal Model:Male C57BL/6J mice Dosage:1 mg/kg Administration:P.o Result:Exhibited sustained plasma exposure.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ELOVL6
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1067647-43-1
  • Formula Weight
    579.49
  • Molecular Formula
    C28H23F6N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:90mg/ml(155.31mM; Need ultrasonic)
  • SMILES
    CC(C)(CC(N1c2ccccc2)=C2C(C(F)(F)F)(C(C3=O)=C(C)NN3c(cc3)ccc3OC(F)(F)F)C1=O)CC2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Synthesis and evaluation of a novel indoledione class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.[J]. Journal of Medicinal Chemistry, 2009, 52(10):3142.
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